Reduced urinary retention using spinal anesthesia with chloroprocaine versus bupivacaine in total joint arthroplasty: A matched retrospective cohort study

Reduced POUR: Chloroprocaine in TJA Chloroprocaine is emerging as a short-acting alternative to bupivacaine for spinal anesthesia in joint arthroplasty. In this retrospective matched cohort study, 50 patients undergoing primary total hip or knee arthroplasty with chloroprocaine were matched to 50 patients receiving bupivacaine. Outcomes included postoperative day 0 ambulation, postoperative urinary retention, and 90-day readmission. Chi-square tests and multivariable logistic regression were used for analysis. Urinary retention was significantly lower with chloroprocaine compared to bupivacaine (4% vs. 22%; p = 0.007). No significant differences were observed in postoperative day 0 ambulation or 90-day readmission rates. Secondary analysis identified younger age as a predictor of early ambulation, while procedure type was associated with reduced urinary retention. Spinal anesthesia with chloroprocaine was associated with a significantly lower incidence of postoperative urinary retention compared with bupivacaine and may be advantageous for patients at risk of this complication.

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Publication Details

Journal
Journal of Orthopaedic Reports
Published
2026-02-01
DOI
https://doi.org/10.1016/j.jorep.2026.100901
Primary Topic
Urinary Tract Infections Management
Type
article
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article

Reduced urinary retention using spinal anesthesia with chloroprocaine versus bupivacaine in total joint arthroplasty: A matched retrospective cohort study

John P. Andrawis, Anthony Arellano-Kruse, Yashodhan Tabib, Félix Pham et al.
Journal of Orthopaedic Reports
Urinary Tract Infections Management
article

Reduced urinary retention using spinal anesthesia with chloroprocaine versus bupivacaine in total joint arthroplasty: A matched retrospective cohort study

John P. Andrawis, Anthony Arellano-Kruse, Yashodhan Tabib, Félix Pham, Dina Hanna, Julie Duong, James Oka
article en

Abstract

Reduced POUR: Chloroprocaine in TJA Chloroprocaine is emerging as a short-acting alternative to bupivacaine for spinal anesthesia in joint arthroplasty. In this retrospective matched cohort study, 50 patients undergoing primary total hip or knee arthroplasty with chloroprocaine were matched to 50 patients receiving bupivacaine. Outcomes included postoperative day 0 ambulation, postoperative urinary retention, and 90-day readmission. Chi-square tests and multivariable logistic regression were used for analysis. Urinary retention was significantly lower with chloroprocaine compared to bupivacaine (4% vs. 22%; p = 0.007). No significant differences were observed in postoperative day 0 ambulation or 90-day readmission rates. Secondary analysis identified younger age as a predictor of early ambulation, while procedure type was associated with reduced urinary retention. Spinal anesthesia with chloroprocaine was associated with a significantly lower incidence of postoperative urinary retention compared with bupivacaine and may be advantageous for patients at risk of this complication.

Journal of Orthopaedic Reports
Torrance Memorial Medical Center (US), Western University of Health Sciences (US)
Good health and well-being
Openalex Percentile: Top 65%
Urinary Tract Infections Management
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Reduced urinary retention using spinal anesthesia with chloroprocaine versus bupivacaine in total joint arthroplasty: A matched retrospective cohort study — John P. Andrawis, Anthony Arellano-Kruse, et al. · Journal of Orthopaedic Reports (2026) | TGRS Research Map | TGRS