Arginase 2 Promotes Colorectal Cancer Metastasis via PI3K/AKT Pathway Activation and Regulates Tumor Immune Infiltration
ARG2 is an independent prognostic marker for CRC. It promotes CRC progression via regulating EMT and PI3K/AKT, holding potential as a novel diagnostic and therapeutic target.
Authors
- Caixia Mo
- Ping Li (ORCID: https://orcid.org/0000-0003-3033-5218)
- Yalin Zhang (ORCID: https://orcid.org/0000-0001-8955-8139)
- Xianwei Mo (ORCID: https://orcid.org/0000-0002-7910-9556)
- Jinmin Hu
- Haixian Shen
- Shanfei Zhou
- Luojuan Wei
- Ning Qu
- Jiale Mei
Institutions
- Guangxi University (CN)
- Guangxi Medical University (CN)
- Tumor Hospital of Guangxi Medical University (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/cam4.71567
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00