Defining frailty using a modified Fried’s Frailty Phenotype in a Southern African context

Culture and language sensitive questions for self-reported exhaustion and weight loss, CHS thresholds for low PA, and population dependent thresholds for GS and WS were the most suitable modifications in a Southern African setting, highlighting the need for region-specific adaptations when diagnosing frailty.

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Publication Details

Journal
PLoS ONE
Published
2026-02-04
DOI
https://doi.org/10.1371/journal.pone.0340723
Primary Topic
Frailty in Older Adults
Type
article
Field-Weighted Citation Impact
0.00

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article

Defining frailty using a modified Fried’s Frailty Phenotype in a Southern African context

B. Cassim, H. Wilson, F. Paruk, A. Mike Burton et al.
PLoS ONE
Frailty in Older Adults
article

Defining frailty using a modified Fried’s Frailty Phenotype in a Southern African context

B. Cassim, H. Wilson, F. Paruk, A. Mike Burton, R. Patel, E. I. Y. Madela, C. L. Gregson, A. M. Manyara, L. Gates, C. Grundy, K. A. Ward, B. Mbanjwa, F. Habana
article en

Abstract

Culture and language sensitive questions for self-reported exhaustion and weight loss, CHS thresholds for low PA, and population dependent thresholds for GS and WS were the most suitable modifications in a Southern African setting, highlighting the need for region-specific adaptations when diagnosing frailty.

PLoS ONEVol. 21(2)
University of Bristol (GB), London School of Hygiene & Tropical Medicine (GB), MRC Lifecourse Epidemiology Unit (GB), University of KwaZulu-Natal (ZA)
Wellcome Trust, National Institute for Health and Care Research, Department of Health and Social Care, Medical Research Council
Openalex Percentile: Top 67%
Frailty in Older Adults
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Defining frailty using a modified Fried’s Frailty Phenotype in a Southern African context — B. Cassim, H. Wilson, et al. · PLoS ONE (2026) | TGRS Research Map | TGRS