Defining frailty using a modified Fried’s Frailty Phenotype in a Southern African context
Culture and language sensitive questions for self-reported exhaustion and weight loss, CHS thresholds for low PA, and population dependent thresholds for GS and WS were the most suitable modifications in a Southern African setting, highlighting the need for region-specific adaptations when diagnosing frailty.
Authors
- B. Cassim
- H. Wilson
- F. Paruk
- A. Mike Burton
- R. Patel
- E. I. Y. Madela
- C. L. Gregson
- A. M. Manyara
- L. Gates
- C. Grundy
- K. A. Ward
- B. Mbanjwa
- F. Habana
Institutions
- University of Bristol (GB)
- London School of Hygiene & Tropical Medicine (GB)
- MRC Lifecourse Epidemiology Unit (GB)
- University of KwaZulu-Natal (ZA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1371/journal.pone.0340723
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- National Institute for Health and Care Research
- Department of Health and Social Care
- Medical Research Council