Bacterial Extracellular Vesicles Mediate Microbiota-Host Communication to Regulate Blood Pressure in Male Rats
Our findings position bEVs as critical mediators of microbiota-host communication in BP regulation and demonstrate that bEVs from the altered SHRSP microbiota promote hypertension. Our findings shed new light on the role of bEVs in hypertension pathogenesis and offer new perspectives for diagnostics and therapeutic interventions.
Authors
- Rishi Wagle
- Blair Mell (ORCID: https://orcid.org/0000-0002-1224-4948)
- Huanan Shi (ORCID: https://orcid.org/0000-0003-3710-5917)
- B. Joe
- Feiya Shi
- David J. Durgan (ORCID: https://orcid.org/0000-0002-3358-1935)
- Blayne A. Oliver (ORCID: https://orcid.org/0000-0001-8185-0215)
- Tianyi Zhu
- Maria Alejandra Gonzalez-Gonzalez
Institutions
- Baylor College of Medicine (US)
- Baylor School (US)
- Neurological Research Institute (US)
- University of Toledo (US)
Publication Details
- Journal
- Hypertension
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25962
- Citations
- 1
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 24.35