Double‐Duty Drugs: Repositioning Antipsychotics to Combat Bacterial Infections

These challenges highlight the need for extensive in vivo and clinical studies to evaluate the antibacterial potential of antipsychotics, ensuring safety and efficacy. Careful monitoring and a balanced risk-benefit analysis are essential when considering antipsychotics for antimicrobial purposes.

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Publication Details

Journal
CNS Neuroscience & Therapeutics
Published
2026-02-01
DOI
https://doi.org/10.1002/cns.70724
Primary Topic
Phenothiazines and Benzothiazines Synthesis and Activities
Type
article
Field-Weighted Citation Impact
0.00
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article

Double‐Duty Drugs: Repositioning Antipsychotics to Combat Bacterial Infections

Sercan Karav, Prashant Kesharwani, Negar Ebadpour, Navid Faraji et al.
CNS Neuroscience & Therapeutics
Phenothiazines and Benzothiazines Synthesis and Activities
article

Double‐Duty Drugs: Repositioning Antipsychotics to Combat Bacterial Infections

Sercan Karav, Prashant Kesharwani, Negar Ebadpour, Navid Faraji, Amirhossein Sahebkar, Mohammad Abavisani
article en

Abstract

These challenges highlight the need for extensive in vivo and clinical studies to evaluate the antibacterial potential of antipsychotics, ensuring safety and efficacy. Careful monitoring and a balanced risk-benefit analysis are essential when considering antipsychotics for antimicrobial purposes.

CNS Neuroscience & TherapeuticsVol. 32(2)
Çanakkale Onsekiz Mart Üniversitesi (TR), Mashhad University of Medical Sciences (IR), Biotechnology Research Center (IR), Chitkara University (IN), Dr. Hari Singh Gour University (IN)
Good health and well-being
Openalex Percentile: Top 67%
Phenothiazines and Benzothiazines Synthesis and Activities
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