Visualization of gadolinium transport across the blood-brain barrier along perivascular clearance pathways

BBB disruption post-DSA may facilitate GBCA transport via glymphatic pathways, offering novel and hypothesis-generating insights into brain clearance mechanisms. GBCA enhancement followed a chronological and spatial pattern, suggesting an organized cerebrospinal-interstitial exchange system relevant for brain clearance. Findings highlight potential implications for BBB integrity in neurovascular health with prospective implications for diagnostic imaging.