Febrile seizure risk following monovalent COVID-19 mRNA vaccination in US children aged 2–5 years

Among children aged 2-5 years, the analysis showed a small elevated incidence rate ratio of febrile seizures in the 0-1 days following the mRNA-1273 vaccination.

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Publication Details

Journal
Vaccine
Published
2026-02-04
DOI
https://doi.org/10.1016/j.vaccine.2026.128225
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
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article

Febrile seizure risk following monovalent COVID-19 mRNA vaccination in US children aged 2–5 years

John D. Seeger, Zhiruo Wan, Yoganand Chillarige, Kandace L. Amend et al.
Vaccine
Long-Term Effects of COVID-19
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Febrile seizure risk following monovalent COVID-19 mRNA vaccination in US children aged 2–5 years

John D. Seeger, Zhiruo Wan, Yoganand Chillarige, Kandace L. Amend, Richard A. Forshee, Kamran Kazemi, Djeneba Audrey Djibo, Lauren Parlett, Mao Hu, Cheryl N. McMahill-Walraven, Jennifer Song, Nandini Selvam, Steven A. Anderson, Alex Secora, Elizabeth R. Smith
article en

Abstract

Among children aged 2-5 years, the analysis showed a small elevated incidence rate ratio of febrile seizures in the 0-1 days following the mRNA-1273 vaccination.

VaccineVol. 75
United States Food and Drug Administration (US), Wilmington University (US), New England College of Optometry (US), Acumen (United States) (US), IQVIA (United States) (US), CVS Health (United States) (US), Optum (United States) (US)
Openalex Percentile: Top 68%
Long-Term Effects of COVID-19
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