A Giant Cervical Decidual Polyp in Pregnancy Managed With Lactoferrin, Probiotics, and Ligation: A Case Report

Giant cervical decidual polyps during pregnancy increase the risk of miscarriage and preterm delivery; however, optimal management has not yet been established. We report the case of a pregnant woman who presented at 11 weeks of gestation with a bleeding 4-cm cervical polyp. Oral lactoferrin and probiotics (<i>Clostridium butyricum</i>, <i>Enterococcus faecium</i>, and <i>Bacillus subtilis</i>) were administered. The polyp stalk near the external cervical os was ligated with triclosan-coated polydioxanone, resulting in necrosis and removal at 13 weeks, with complete resolution by 14 weeks. Vaginal <i>Lactobacillus</i> spp. increased and cervicitis resolved by 20 weeks without the use of antibiotics, despite the presence of <i>Ureaplasma</i> and/or <i>Mycoplasma</i> in vaginal secretions. The patient delivered a healthy infant at 40 weeks. This case highlights a minimally invasive strategy-polyp ligation combined with lactoferrin and probiotics-to help restore vaginal homeostasis, avoid the use of antibiotics, and achieve a favorable pregnancy outcome.