β-Adrenergic Signaling Contributes to Circadian and Lipid Dysregulation in Meibomian Glands During Chronic Psychological Stress
Chronic psychological stress disrupts MG homeostasis through sympathetic overactivation, affecting circadian regulation, immune responses, and lipid metabolism. β-Adrenergic blockade partially reverses these changes, highlighting a potential therapeutic approach for stress-related evaporative dry eye.
Authors
- Di Qi (ORCID: https://orcid.org/0000-0003-4762-266X)
- Jing‐Wen Yang (ORCID: https://orcid.org/0000-0002-7031-3446)
- Wenxiao Zhang (ORCID: https://orcid.org/0000-0001-8680-6010)
- Mengru Ba
- Xiaoting Pei (ORCID: https://orcid.org/0000-0001-7342-7572)
- Dingli Lu
- Shuting Xuan
- Duliurui Huang
- Jing Li (ORCID: https://orcid.org/0009-0003-6354-6975)
- Tingting Yang
- Zhijie Li
- Shenzhen Huang
Institutions
- Henan University (CN)
- Zhengzhou University (CN)
- Henan Provincial People's Hospital (CN)
- Henan Provincial Eye Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1167/iovs.67.2.15
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00