Spatial proteomics reveals layer-specific molecular landscapes and keratin 17-mediated inflammatory crosstalk in oral lichen planus of the tongue
Our study uncovers layer-specific molecular landscapes in tongue OLP and identifies KRT17 as a candidate implicated in immune-epithelial crosstalk, providing novel insights into pathogenesis and a potential direction for future therapeutic exploration.
Authors
- MU Sen
- Zhang SongWei
- Yan Wang (ORCID: https://orcid.org/0000-0003-3664-7933)
- Yan Ying
- Zhang Zhuoran
- Miao Nan
- Wang Qian
- Zhang Qianyang
- Xia Yunfei
- Yang Chubo
- Li Huishu
- Zhan Yuanbo
- Kong Jiaqi
- Huang Yaping
- Wang Mingxing
- Gao Li
Institutions
- Harbin Medical University (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
- Suzhou Vocational Health College (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1093/bjd/ljag040
- Primary Topic
- Oral Health Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00