Randomised Controlled Trial on the Additive Effect Between Calcium Hydroxide and Sodium Hypochlorite in an Inter-Visit Root Canal Dressing

Aim: To assess whether there was an additive antimicrobial effect between calcium hydroxide (Ca(OH)) and sodium hypochlorite (NaOCl) in an inter-visit root canal dressing. Conclusions: Placing a combined NaOCl/Ca(OH) dressing significantly reduced the microbial load in the root canals of teeth with primary apical periodontitis compared to a conventional slurry prepared with saline solution, without causing any apparent inflammatory response in the periapical tissues. Trial registeration: CTRI/2020/10/028484 (Clinical Trials Registry India).