Prognostic impact of individual resection and dissection margins in resected perihilar cholangiocarcinoma: retrospective study
This study found that only tumour infiltration of the proximal bile duct resection margin was associated with worse prognosis, most likely reflecting the malignant behaviour of the disease rather than surgical failure. Larger prospective studies are needed to clarify the true prognostic impact of residual disease in individual resection planes to allocate patients to specific chemotherapeutic (neo)adjuvant treatments.
Authors
- C. Sturesson
- Lotte C. Franken (ORCID: https://orcid.org/0000-0002-2154-4571)
- J. Erdmann
- Hasan Ahmad Al-Saffar (ORCID: https://orcid.org/0009-0008-6507-375X)
- Eva Roos (ORCID: https://orcid.org/0000-0002-9912-6409)
- Heinz-Josef Klümpen
- Joanne Verheij (ORCID: https://orcid.org/0000-0003-1283-630X)
- Mahsoem Ali
- Geert Kazemier
- Britte H E A ten Haaft
- Lynn Nooijen
- Carlos Fernandez Moro
Institutions
- Karolinska University Hospital (SE)
- Copenhagen University Hospital (DK)
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- Amsterdam University of Applied Sciences (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- BJS Open
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1093/bjsopen/zraf160
- Citations
- 1
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.01