Management of moderate and severe ovarian hyperstimulation syndrome (OHSS): a Canadian Fertility and Andrology Society (CFAS) clinical practice guideline
<h2>Abstract</h2> Ovarian hyperstimulation syndrome (OHSS) is a potentially serious complication associated with ovarian stimulation for assisted reproductive technology (ART). While measures to prevent and reduce the incidence of OHSS are part of good clinical practice, OHSS still occurs, and patients may present to clinicians with varying familiarity with the condition. Diagnosis is largely clinical, although radiological and laboratory testing help determine the severity of the syndrome. Management of moderate and severe OHSS is primarily supportive either as an outpatient or as an inpatient and may include paracentesis. Critical OHSS needs hospitalization and multidisciplinary care. This clinical practice guideline assesses the published evidence regarding the diagnosis and management of patients presenting with moderate and severe OHSS.
Authors
- Camille Sylvestre (ORCID: https://orcid.org/0000-0003-0299-3766)
- Neal Mahutte (ORCID: https://orcid.org/0000-0002-6619-0172)
- Kimberly Liu (ORCID: https://orcid.org/0000-0002-8640-4414)
- W. R. Buckett
- Sony Sierra
- Jeff Roberts
- Maria P Velez
- Julio Saumet
- Jason Min
Institutions
- University of Calgary (CA)
- University of Toronto (CA)
- Pacific Centre for Reproductive Medicine (CA)
- Ottawa Fertility Centre (CA)
- CReATe Fertility Centre (CA)
- McGill University (CA)
Publication Details
- Journal
- Reproductive BioMedicine Online
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.rbmo.2026.105541
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00