Non-implantable neuromodulation therapies compared to conventional treatments for major depression
Non-implantable neuromodulation therapies are evolving from experimental interventions to validated clinical options. Rather than competing with pharmacotherapy, they should be viewed as complementary components within a multimodal framework. The future of depression management likely depends on the integration of pharmacological and neuromodulatory approaches to optimize response, tolerability, and functional recovery.
Authors
- Vitor Breseghello Cavenaghi
- Eric Cretaz (ORCID: https://orcid.org/0000-0001-7777-8660)
- Kallene Summer Moreira Vidal (ORCID: https://orcid.org/0000-0003-4559-2612)
- Rebeca Pelosof (ORCID: https://orcid.org/0000-0001-5718-5147)
- Valquiria Aparecida Silva
- André Russowsky Brunoni
- Victor Fontenelle Bastos Lima
- Vanessa Malfatti
Institutions
- Universidade de São Paulo (BR)
- Southwestern Medical Center (US)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Expert Review of Clinical Pharmacology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1080/17512433.2026.2626459
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00