Time-Dependent Glucocorticoid-Induced Transcriptomic Changes in Human Trabecular Meshwork and Schlemm's Canal Cells

This study identified candidate genes and pathways for glucocorticoid-induced ocular hypertension which can be further explored in human genetic analyses.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2026-02-04
DOI
https://doi.org/10.1167/iovs.67.2.13
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Time-Dependent Glucocorticoid-Induced Transcriptomic Changes in Human Trabecular Meshwork and Schlemm's Canal Cells

Hilary Scott, Katie Huynh, Atitaya Apivatthakakul, Kristin Perkumas et al.
Investigative Ophthalmology & Visual Science
Glaucoma and retinal disorders
article

Time-Dependent Glucocorticoid-Induced Transcriptomic Changes in Human Trabecular Meshwork and Schlemm's Canal Cells

Hilary Scott, Katie Huynh, Atitaya Apivatthakakul, Kristin Perkumas, H Jeanneret, Ananya Mukundan, Sudeep Mehrotra, Jyoti Lama, Ayellet V. Segrè, Lucia Sobrin, Renee Liu, Janey L. Wiggs, W. Daniel Stamer
article en

Abstract

This study identified candidate genes and pathways for glucocorticoid-induced ocular hypertension which can be further explored in human genetic analyses.

Investigative Ophthalmology & Visual ScienceVol. 67(2)
Massachusetts Eye and Ear Infirmary (US), Harvard University (US), North Carolina State University (US), Duke University (US), Chiang Mai University (TH)
Research to Prevent Blindness, Massachusetts Eye and Ear, National Institutes of Health
Zero hunger
Openalex Percentile: Top 67%
Glaucoma and retinal disorders
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