Analysis of Keratoconus-Related Phenotypes in Two Pcsk1 Mouse Models
Genetic factors are known to contribute to the pathogenesis of keratoconus. Although a variant in the Pcsk1 gene has been shown to segregate with keratoconus in a family, there is yet no evidence of Pcsk1 gene mutation correlating with pathogenic corneal phenotype in mouse models.
Authors
- SI Patel
- Hongfang Yu
- Ashlie Bernhisel (ORCID: https://orcid.org/0000-0002-6692-2281)
- Yutao Liu
- Keith H. Baratz (ORCID: https://orcid.org/0000-0002-0676-7646)
- Amy Estes
- Anthony N. Kuo
- C. H. Beatty
- Jiong Sun
- Yejin Heo
- Jingwen Cai
Institutions
- Augusta University (US)
- Discovery Institute (US)
- Mayo Clinic in Arizona (US)
- Duke Medical Center (US)
Publication Details
- Journal
- Translational Vision Science & Technology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1167/tvst.15.2.3
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00