Wuji Pill and Akkermansia muciniphila alleviates intestinal dysfunction and depression-like behavior in irritable bowel syndrome through the microbiota-gut-brain axis
This study highlights the Wuji Pill may alleviate IBS symptoms by modulating <i>A. muciniphila</i> and regulating the tryptophan metabolism pathway through MGB axis.
Authors
- Mengting Li (ORCID: https://orcid.org/0000-0002-2527-5196)
- Pengyue Li (ORCID: https://orcid.org/0000-0003-1156-2423)
- T. Li
- Q Li
- Zipeng Gong
- Xiaoxin Zhu (ORCID: https://orcid.org/0000-0003-2948-3395)
- Lijinchuan Dong
- Yu Dong (ORCID: https://orcid.org/0000-0002-4836-4933)
- Yuxing Wang (ORCID: https://orcid.org/0000-0003-3079-5572)
- Shuiming Xiao
- Qi Li (ORCID: https://orcid.org/0000-0001-9181-1391)
- Yajie Wang
- Yujie Li
- Yuxuan Guo
- Xiaogang Weng
- Zhe Shi
- Bo Peng
- Qin Hu
- Ying Chen
- Qing Yang
Institutions
- Guiyang Medical University (CN)
- Hunan University of Traditional Chinese Medicine (CN)
- Beijing University of Technology (CN)
- China Academy of Chinese Medical Sciences (CN)
- Guang’anmen Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.3389/fmicb.2026.1739408
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00