Recurrent Laryngeal Nerve Stretching in Tracheal Diverticulum: First Documented Mechanism of Hoarseness and Systematic Review of Literatures

Tracheal diverticulum is a rare paratracheal air cyst. It is often asymptomatic. Large symptomatic cases may compress the recurrent laryngeal nerve (RLN) and cause hoarseness. It is a rare presentation, in < 0.2 cases per year in the world. We present a 45-year-old woman that had 6 months of chronic cough, dysphagia, odynophagia, dyspnea, hoarseness, hemoptysis, choking, and neck pain. She was not a smoker. Spirometry showed mild obstruction pattern (FEV1 78%). CT with 3D reconstruction revealed a 4 × 5 cm right posterolateral tracheal diverticulum (fifth-seventh rings, 8 mm communication). Bronchoscopy confirmed limited right vocal cord mobility. We did an open cervical excision that preserved the RLN. Histopathology confirmed acquired diverticulum. Hoarseness resolved in 3 weeks; repeat bronchoscopy showed normal vocal cord mobility. 3-month CT confirmed resolution; 1-year FEV1 improved. Asymptomatic at 12 months. Systematic review (1998-2025) found 4 prior hoarseness cases (total <i>n</i> = 5): 60% female, 80% right posterolateral, mean size 3.0 cm, 80% complete recovery in 3 weeks via open surgery. Largest reported diverticulum is with hoarseness. This is the first case with documentation of RLN stretching and quantitative improvement with spirometry. Multimodal imaging and early open excision with nerve preservation can cause excellent outcomes.

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Journal
Clinical Case Reports
Published
2026-02-01
DOI
https://doi.org/10.1002/ccr3.71885
Primary Topic
Tracheal and airway disorders
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article
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article

Recurrent Laryngeal Nerve Stretching in Tracheal Diverticulum: First Documented Mechanism of Hoarseness and Systematic Review of Literatures

Zahra Sadin, mohammadreza sadin, Manouchehr Aghajanzadeh
Clinical Case Reports
Tracheal and airway disorders
article

Recurrent Laryngeal Nerve Stretching in Tracheal Diverticulum: First Documented Mechanism of Hoarseness and Systematic Review of Literatures

Zahra Sadin, mohammadreza sadin, Manouchehr Aghajanzadeh
article en

Abstract

Tracheal diverticulum is a rare paratracheal air cyst. It is often asymptomatic. Large symptomatic cases may compress the recurrent laryngeal nerve (RLN) and cause hoarseness. It is a rare presentation, in < 0.2 cases per year in the world. We present a 45-year-old woman that had 6 months of chronic cough, dysphagia, odynophagia, dyspnea, hoarseness, hemoptysis, choking, and neck pain. She was not a smoker. Spirometry showed mild obstruction pattern (FEV1 78%). CT with 3D reconstruction revealed a 4 × 5 cm right posterolateral tracheal diverticulum (fifth-seventh rings, 8 mm communication). Bronchoscopy confirmed limited right vocal cord mobility. We did an open cervical excision that preserved the RLN. Histopathology confirmed acquired diverticulum. Hoarseness resolved in 3 weeks; repeat bronchoscopy showed normal vocal cord mobility. 3-month CT confirmed resolution; 1-year FEV1 improved. Asymptomatic at 12 months. Systematic review (1998-2025) found 4 prior hoarseness cases (total <i>n</i> = 5): 60% female, 80% right posterolateral, mean size 3.0 cm, 80% complete recovery in 3 weeks via open surgery. Largest reported diverticulum is with hoarseness. This is the first case with documentation of RLN stretching and quantitative improvement with spirometry. Multimodal imaging and early open excision with nerve preservation can cause excellent outcomes.

Clinical Case ReportsVol. 14(2)
Guilan University of Medical Sciences (IR), Razi Hospital (IR)
Good health and well-being
Openalex Percentile: Top 68%
Tracheal and airway disorders
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Recurrent Laryngeal Nerve Stretching in Tracheal Diverticulum: First Documented Mechanism of Hoarseness and Systematic Review of Literatures — Zahra Sadin, mohammadreza sadin, et al. · Clinical Case Reports (2026) | TGRS Research Map | TGRS