A frequency-spatial dual perception network for efficient and accurate medical image segmentation
The acquisition mechanism of medical images differs from that of natural images, consequently enabling frequency-domain information to reveal deeper-level pathological features in medical image analysis. However, extracting the significant pathological features from diverse frequency domains remain a core challenge in medical image segmentation. In this paper, we proposed an efficient medical image segmentation network, called FDE-Net, that effectively utilizes frequency-domain information. First, a Low-Frequency Information Extraction Block (LFIEB) is designed to selectively enhance critical information in frequency-domain features, thereby extracting the most discriminative pathological features. Furthermore, for seamless integration of frequency-domain and spatial features, a Multi-head Perception Visual State Space (MPVSS) is adopted with structural optimizations implemented to significantly improve multi-scale spatial feature extraction capabilities. Finally, a U-shaped network architecture was constructed, incorporating the Context Focus Attention (CFA) module to more efficiently propagate shallow features to the decoder. We validate FDE-Net on three publicly available medical image datasets. On ISIC-2018, our method achieves 84.10% IoU and 91.29% DSC, surpassing UNet by 6.24% and 3.74%, respectively, while maintaining computational efficiency. Comprehensive ablation studies confirm the individual contributions of the LFIEB and MPVSS modules. These results demonstrate that FDE-Net effectively balances segmentation accuracy and computational efficiency, making it promising for clinical deployment.
Authors
- Xuyao Zhang (ORCID: https://orcid.org/0000-0003-1654-5550)
- Jiahua Wu
- Daxin Chen
- Da-Han Wang
Institutions
- Xiamen University (CN)
- Chinese Academy of Sciences (CN)
- Institute of Automation (CN)
- Xiamen University of Technology (CN)
Publication Details
- Journal
- Scientific Reports
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1038/s41598-026-38093-7
- Primary Topic
- Advanced Neural Network Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Xiamen University