Prevalence and predictors of residual gastric content in patients with type 2 diabetes on <scp>GLP</scp> ‐1 receptor agonists: A prospective observational study

GLP-1 RA therapy is a potent, independent driver of significant gastric retention in patients with T2DM, persisting despite standard fasting. Crucially, the presence of diabetic retinopathy or nephropathy identifies a "double-hit" high-risk phenotype, where pharmacological delay interacts with microvascular burden. These findings suggest that current fasting protocols may be insufficient for these patients, necessitating individualized preoperative assessment based on microvascular status and dosing timing.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-02-03
DOI
https://doi.org/10.1111/dom.70537
Citations
1
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
30.73
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article

Prevalence and predictors of residual gastric content in patients with type 2 diabetes on GLP ‐1 receptor agonists: A prospective observational study

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1 citations
Diabetes Obesity and Metabolism
Diabetes Treatment and Management
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article

Prevalence and predictors of residual gastric content in patients with type 2 diabetes on GLP ‐1 receptor agonists: A prospective observational study

Bin Lü, Jin Li, Xiaofeng Li, Yun Jin, Xiu‐ye Feng, Jin‐ying Xia, Ye‐ping Mo, Xiao‐jie Zhai, Jun‐ping Chen, Rui‐chun Wang, Fan‐fu Zeng, Jin‐ling Qin
article en
1 citations

Abstract

GLP-1 RA therapy is a potent, independent driver of significant gastric retention in patients with T2DM, persisting despite standard fasting. Crucially, the presence of diabetic retinopathy or nephropathy identifies a "double-hit" high-risk phenotype, where pharmacological delay interacts with microvascular burden. These findings suggest that current fasting protocols may be insufficient for these patients, necessitating individualized preoperative assessment based on microvascular status and dosing timing.

Diabetes Obesity and Metabolism
Ningbo Center for Disease Control and Prevention (CN), Ningbo No. 2 Hospital (CN), Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine (CN), Ningbo University Affiliated Hospital (CN), Ningbo No.6 Hospital (CN), Ningbo First Hospital (CN)
Openalex Percentile: Top 1%
Diabetes Treatment and Management
30.73
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