VPA targets Mid1 to improve disrupted retrograde axonal transport in hippocampal neurons and alleviate lithium manganate-induced learning and memory dysfunction
This study indicates that LMO inhalation exposure is associated with learning and memory deficits and hippocampal neuronal injury, accompanied by Mid1-related ubiquitin-proteasome alterations and disrupted retrograde axonal transport.
Authors
- Zhushan Fu
- Yueqing Song
- Wenhao Li
- Yi Wen
- Yu Deng
- Yue Chen
- Xinmiao Wang
- Zhaohe Ju
- Jingqi Chen
- Yantong Chen
Institutions
- China Medical University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jare.2026.01.081
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00