A computationally frugal, open-source chest CT foundation model for thoracic disease detection in lung cancer screening programmes
TANGERINE's accessible, open-source, lightweight design lays the foundation for rapid integration into next-generation medical imaging tools, enabling lung cancer screening programmes to pivot from a singular focus on lung cancer detection toward comprehensive respiratory disease management in high-risk populations.
Authors
- Elena Stefan
- Ethaar El-Emir
- Amyn Bhamani (ORCID: https://orcid.org/0000-0002-8575-6119)
- Daryl Cheng (ORCID: https://orcid.org/0000-0001-9906-4298)
- Thea Buchan
- Hina Pervez
- Terry O’Shaughnessy
- April Q Neville
- Simranjit Mehta
- Jane Rowlands
- N. Nundlall
- H Kiconco
- Priyam Verghese (ORCID: https://orcid.org/0000-0002-1319-3986)
- Shahab Zeini Aslani
- Pardeep Vasudev
- Karen Parry-Billings
- Nicholas Beech (ORCID: https://orcid.org/0000-0003-3843-0252)
- Niccolò McConnell
- Dominique Arancon (ORCID: https://orcid.org/0000-0003-3904-6551)
- Fahmida Hoque
- William Ricketts (ORCID: https://orcid.org/0000-0002-0475-0744)
- Ricardo McEwen (ORCID: https://orcid.org/0000-0002-9591-343X)
- Ugo Ekeowa
- Sophie Tisi
- Jennifer Dickson (ORCID: https://orcid.org/0000-0002-9333-8320)
- Kate H.C. Gowers (ORCID: https://orcid.org/0000-0002-3481-4016)
- Charlotte Cash
- Andrew Perugia
- Geoff Bellingan (ORCID: https://orcid.org/0000-0003-4193-4689)
- Vicky Bowyer
- Claire Levermore (ORCID: https://orcid.org/0000-0003-4026-824X)
- Jeannie Eng (ORCID: https://orcid.org/0000-0002-7592-4246)
- Thomas Callender (ORCID: https://orcid.org/0000-0001-8440-9433)
- C. C. Nestor (ORCID: https://orcid.org/0000-0001-5061-9950)
- James Rusius
- Aashna Samson
- Maureen Browne
- Esther Arthur-Darkwa
- Janine Zylstra (ORCID: https://orcid.org/0000-0002-9839-7629)
- Tania Anastasiadis
- Derya Ovayolu
- Kate Davies
- Hasti Robbie (ORCID: https://orcid.org/0000-0001-5108-5268)
- Ruth Prendecki
- Graham Robinson (ORCID: https://orcid.org/0000-0003-1991-1835)
- U. Patel (ORCID: https://orcid.org/0009-0000-8134-3811)
- Rajesh Banka
- Mark E. Clark (ORCID: https://orcid.org/0000-0002-5660-2153)
- Charlie Sayer
- Magali Taylor
- Christie Ife
- Sofia Nnorom
- Sheetal Karavadra
- Carolyn Anne Kirby Horst
- Anne-Marie Hacker
- Z. Hanif
- Samanjit S Hare
- Eleanor Hellier
- Judy Airebamen
- Christine Hosein
- Sylvia Patricia Enes
- Andrew Crossingham
- Tanita Limani
- Anand Devaraj
- Lynsey Gallagher
- Sara Lock
- Nick Screaton
- Ahmed H. Shahin
- Daniel C. Alexander
- Samantha L. Quaife
- Helen Hall
- Alice Cotton
- Monica L. Mullin
- Angshu Bhowmik
- Joseph Jacob
- Mehran Azimbagirad
- Julian McKee
- Yipeng Hu
- Alan Shaw
- Moksud Miah
- Elodie Murali
- Tanya Patrick
- Kylie Gyertson
- Daisuke Yamada
- Tunku Aziz
- Andre Altmann
- Paul Taylor
- Ali Mohammed
- Allan Hackshaw
- Yukun Zhou
- Stephen Ellis
- Chris Valerio
- Alberto Villanueva
- Mamta Ruparel
- Anthony Edey
- Chuen Khaw
- Arjun Nair
- Sam M. Janes
- Paul Robinson
- Anant Patel
- John McCabe
- Fanta Bojang
- Burcu Ozaltin
- Andrew Creamer
- Neal Navani
- Kaylene Phua
- Laura Green
Institutions
- Universities UK (GB)
- Hawassa University (ET)
- Nickel Institute (CA)
- Health Data Research UK (GB)
- The London College (GB)
- University College London (GB)
Publication Details
- Journal
- Communications Medicine
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1038/s43856-025-01328-1
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00