A Spectroscopic Tour of Molecular Interactions in the Micelle Induced Solubilization of Thymol Based Schiff Bases

ABSTRACT The thymol based Schiff bases (Sbs) were proved to be a well‐known probe possessing photophysical characteristics under the reinforcement of absorption and fluorescence spectroscopy. This further enlightens our zeal to work on these probes in aqueous solutions of Cetyltrimethylammonium bromide (CTAB), Sodium dodecyl sulfate (SDS) and Triton X‐100 (TX‐100), respectively. The well‐known instruments spectrophotometer and spectrofluorometer were used to observe the absorption and fluorescence spectral measurements in aqueous surfactants medium. Solubilization studies explored how well a probe dissolves or disperses in different media thereby influencing its photophysical properties. The obtained critical micellar concentration (CMC) values showed coherence with their literature values. The large binding constants (K b ) ranging 10 6 revealed good synergy between Sbs and the studied micelles. These findings reveal distinct solubilization patterns that are influenced by electrostatic interactions and the nature of micellar assemblies. These Sbs reside in the hydrophilic–hydrophobic peripheral regions in case of SDS and CTAB, quite the reverse, they get housed in the palisade layer of TX‐100. The negative ΔG mic and ΔG b values corroborate spontaneity and stability of the micellization process. This research highlights the prospect of aqueous micellar systems connotation with the principles of green chemistry (GC) and some of the Sustainable Development Goals.