The hidden burden of kidney damage in chylomicronemia syndromes

These data suggest that severe chylomicronemia due to FCS and MCS is predominantly associated with proteinuria, which might be the possible consequences of lipid-laden glomerular injury. Therefore, renal disease should be included in the list of possible complications of severe chylomicronemia, thus suggesting that renal monitoring have to be considered as part of clinical management of these conditions.

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Publication Details

Journal
Atherosclerosis
Published
2026-02-01
DOI
https://doi.org/10.1016/j.atherosclerosis.2025.120621
Primary Topic
Lipid metabolism and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

The hidden burden of kidney damage in chylomicronemia syndromes

C Bruna, Daniela Commodari, Valeria Pecce, Daniele Tramontano et al.
Atherosclerosis
Lipid metabolism and disorders
article

The hidden burden of kidney damage in chylomicronemia syndromes

C Bruna, Daniela Commodari, Valeria Pecce, Daniele Tramontano, S. Bini, Ilenia Minicocci, Marcello Arca, Ina Arizaj, Laura D'Erasmo, Diane Brisson, Miriam Larouche, Marzia Pasquali, Loreto Gesualdo, Daniel Gaudet, Alessia Di Costanzo
article en

Abstract

These data suggest that severe chylomicronemia due to FCS and MCS is predominantly associated with proteinuria, which might be the possible consequences of lipid-laden glomerular injury. Therefore, renal disease should be included in the list of possible complications of severe chylomicronemia, thus suggesting that renal monitoring have to be considered as part of clinical management of these conditions.

AtherosclerosisVol. 413
Policlinico Umberto I (IT), University of Bari Aldo Moro (IT), Université de Montréal (CA), Sapienza University of Rome (IT)
Good health and well-being
Openalex Percentile: Top 67%
Lipid metabolism and disorders
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