A green-electrospun nanofibrous scaffold incorporating polyethylenimine-modified liposomes for sustained BMP2 gene delivery and enhanced osteogenic differentiation
The novel composite scaffold combines the structural advantages of SF with a sustained BMP2 gene delivery system, showing remarkable potential to promote osteogenic differentiation. This work presents a promising, environmentally friendly, and effective platform for bone tissue engineering and regenerative medicine.
Authors
- Shasha Duan (ORCID: https://orcid.org/0000-0002-1562-9579)
- L Zhang
- Hongsheng Wang (ORCID: https://orcid.org/0000-0003-0079-0236)
- Shuqi Lou
- Zhen Chen
- Mengxia Chen
- Sunfei Chen
Institutions
- Donghua University (CN)
- Shanghai Stomatological Hospital (CN)
- Shaoxing No.6 People's Hospital (CN)
- Shaoxing People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.3389/fbioe.2026.1748649
- Primary Topic
- Silk-based biomaterials and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00