Effects of Dual Orexin Receptor Antagonists on Seizure Quality in Modified Electroconvulsive Therapy

DORA use during m-ECT did not impair seizure quality, supporting their safe concomitant use. Findings were consistent across subgroup, agent, and dose-response analyses. Larger prospective trials are warranted to confirm these results.

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Publication Details

Journal
Journal of Ect
Published
2026-02-04
DOI
https://doi.org/10.1097/yct.0000000000001223
Primary Topic
Sleep and Wakefulness Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Effects of Dual Orexin Receptor Antagonists on Seizure Quality in Modified Electroconvulsive Therapy

Yuichi Shimohara, Taro Matsuda, Kazuhiko Iwata
Journal of Ect
Sleep and Wakefulness Research
article

Effects of Dual Orexin Receptor Antagonists on Seizure Quality in Modified Electroconvulsive Therapy

Yuichi Shimohara, Taro Matsuda, Kazuhiko Iwata
article en

Abstract

DORA use during m-ECT did not impair seizure quality, supporting their safe concomitant use. Findings were consistent across subgroup, agent, and dose-response analyses. Larger prospective trials are warranted to confirm these results.

Journal of Ect
Artistic Realization Technologies (US)
Openalex Percentile: Top 67%
Sleep and Wakefulness Research
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Effects of Dual Orexin Receptor Antagonists on Seizure Quality in Modified Electroconvulsive Therapy — Yuichi Shimohara, Taro Matsuda, et al. · Journal of Ect (2026) | TGRS Research Map | TGRS