Integrative single‐cell analysis uncovers distinct tumour microenvironment ecotypes and immune evasion across skin cancers

This study establishes a pan-skin cancer immune remodelling framework, providing a foundation for biomarker discovery and the development of new immunotherapy strategies.

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Publication Details

Journal
Clinical and Translational Medicine
Published
2026-02-01
DOI
https://doi.org/10.1002/ctm2.70611
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
0.00

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article

Integrative single‐cell analysis uncovers distinct tumour microenvironment ecotypes and immune evasion across skin cancers

Shiyao Pei, Haoqiu Song, Wensheng Shi, L. Dong et al.
Clinical and Translational Medicine
Single-cell and spatial transcriptomics
article

Integrative single‐cell analysis uncovers distinct tumour microenvironment ecotypes and immune evasion across skin cancers

Shiyao Pei, Haoqiu Song, Wensheng Shi, L. Dong, Shenglin Mei, Huihui Hou, Xiaofeng Li, Jiayu Sun, Lingjuan Huang, M. Yin, Xiang Chen, Anil Prakash, Mason Liu
article en

Abstract

This study establishes a pan-skin cancer immune remodelling framework, providing a foundation for biomarker discovery and the development of new immunotherapy strategies.

Clinical and Translational MedicineVol. 16(2)
Central South University (CN), Chongqing University (CN), American Institute for Cancer Research (US), Thomas College (US), Virginia–Maryland College of Veterinary Medicine (US), SKiN Health (CA), Hunan Cancer Hospital (CN), Chongqing Three Gorges Central Hospital (CN), Chongqing Emergency Medical Center (CN), Sanya University (CN), Second Xiangya Hospital of Central South University (CN), Chongqing Cancer Hospital (CN), Third Xiangya Hospital (CN), Chongqing Three Gorges University (CN), Southern Medical University (CN), Virginia Tech (US)
Centre Scientifique et Technique du Bâtiment
Life in Land
Openalex Percentile: Top 67%
Single-cell and spatial transcriptomics
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Integrative single‐cell analysis uncovers distinct tumour microenvironment ecotypes and immune evasion across skin cancers — Shiyao Pei, Haoqiu Song, et al. · Clinical and Translational Medicine (2026) | TGRS Research Map | TGRS