Harnessing nucleotide metabolism to control glycosylase base editing outcomes
Our findings establish metabolic modulation as a powerful means to control base editing outcomes and expand the functional capabilities of glycosylase-derived editors.
Authors
- Yaoge Jiao
- Rui Tao (ORCID: https://orcid.org/0000-0002-3604-0704)
- Minhai Tang
- Yun Hu
- Zhi Yang
- Shaohua Yao
- Zhangxue Hu
- Min Li
- Junyi Fei
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Health and Family Planning Commission of Sichuan Province (CN)
Publication Details
- Journal
- Theranostics
- Published
- 2026-02-04
- DOI
- https://doi.org/10.7150/thno.125705
- Primary Topic
- CRISPR and Genetic Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Postdoctoral Science Foundation
- Sichuan University
- West China Hospital, Sichuan University