Association between aerobic exercise and vascular endothelial growth factor (VEGF) concentration in adults: a systematic review and meta-analysis of randomized controlled trials

It appears that aerobic exercise does not have significant overall influence on circulating VEGF levels. However, VEGF reductions may subsequently occur after short-duration interventions. Further research is needed with larger high-quality RCTs to verify these associations and further explore the mechanisms.

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Publication Details

Journal
BMC Sports Science Medicine and Rehabilitation
Published
2026-02-04
DOI
https://doi.org/10.1186/s13102-026-01565-4
Primary Topic
Angiogenesis and VEGF in Cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between aerobic exercise and vascular endothelial growth factor (VEGF) concentration in adults: a systematic review and meta-analysis of randomized controlled trials

Reza Amiri Khosroshahi, Sam Bayat, Amir Hossein Zanganeh, Nazanin Zamanian et al.
BMC Sports Science Medicine and Rehabilitation
Angiogenesis and VEGF in Cancer
article

Association between aerobic exercise and vascular endothelial growth factor (VEGF) concentration in adults: a systematic review and meta-analysis of randomized controlled trials

Reza Amiri Khosroshahi, Sam Bayat, Amir Hossein Zanganeh, Nazanin Zamanian, Ali Asadolah, Rahman Soori, Reza Ghorbani Khosroshahi, Nima Ahani, Pardis Darabi
article en

Abstract

It appears that aerobic exercise does not have significant overall influence on circulating VEGF levels. However, VEGF reductions may subsequently occur after short-duration interventions. Further research is needed with larger high-quality RCTs to verify these associations and further explore the mechanisms.

BMC Sports Science Medicine and RehabilitationVol. 18(1)
Tabriz University of Medical Sciences (IR), University of Tehran (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 68%
Angiogenesis and VEGF in Cancer
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