What Are the Limitations of Measuring Bladder Compliance, As the Sole Indicator of Future Risk to the Upper Urinary Tract and Renal Function? ICI‐RS 2025

Prediciting upper urinary tract deterioration due to abnormalities of bladder compliance remains inexact as an isolated metric. The reasons for the lack of sensitivity and specificity are not well understood. Identifying the limitations of bladder compliance, modifying its assessment or combining it with other clinical or biological measurements may provide better and more precise prognostic information. In the meantime, advice is given on a "common sense" way by which UDS can be modified in relevant patient, in order to provide information that improves management and surveillance of vulnerable patients at risk from renal damage.