Statin-associated symptoms and statin intolerance in children with familial hypercholesterolemia: Insights from 15 years of clinical practice

This study shows that SAS were common, but generally transient and mild, whereas statin into-lerance was relatively uncommon in children with FH. Proactive management of SAS and consideration of alternative therapies are crucial to maintain adherence and reduce their increased cardiovascular risk. Future research should focus on identifying risk factors to enable personalized treatment strategies.