Comprehensive analysis of molecular immunological characteristics and potential biomarkers in brucellosis
These novel hub genes are closely implicated in inflammatory responses, neutrophil regulation, and B cell receptor signaling pathways-key processes underlying brucellosis pathogenesis that have not been previously targeted for diagnostic biomarker development. This work not only enhances our understanding of brucellosis biology but also lays a critical foundation for the development of non-invasive, accurate diagnostic tools and targeted therapeutic strategies-filling a significant gap in current brucellosis management.
Authors
- Rui Wang (ORCID: https://orcid.org/0000-0003-1723-4746)
- Li Xiao (ORCID: https://orcid.org/0000-0002-5488-5583)
- Juan He (ORCID: https://orcid.org/0000-0002-6485-1336)
- Haitao Ding (ORCID: https://orcid.org/0000-0001-6200-6940)
- Yue Shi (ORCID: https://orcid.org/0000-0002-2574-7229)
- Huijuan Duan
Institutions
- Mongolian Academy of Sciences (MN)
- Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences (CN)
- Inner Mongolia People's Hospital (CN)
- Inner Mongolia Medical College Hospital (CN)
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.3389/fimmu.2026.1614025
- Primary Topic
- Brucella: diagnosis, epidemiology, treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00