Associations between serological evidence of SARS-CoV-2 infection and longitudinal pulmonary outcomes among people with HIV: analysis of the MACS/WIHS combined cohort study (MWCCS)

Among individuals with serologic evidence of SARS-CoV-2 infection, HIV serostatus was not associated with greater declines in pulmonary function or worsening of respiratory symptoms. Our findings suggest that having HIV alone may not increase the risk for pulmonary impairments following a SARS-CoV-2 infection. Further research is needed to understand how uncontrolled HIV infection and severity of SARS-CoV-2 infection may increase risks of adverse pulmonary outcomes following a SARS-CoV-2 infection.

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Publication Details

Journal
Respiratory Research
Published
2026-02-05
DOI
https://doi.org/10.1186/s12931-026-03542-4
Primary Topic
Pneumocystis jirovecii pneumonia detection and treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Associations between serological evidence of SARS-CoV-2 infection and longitudinal pulmonary outcomes among people with HIV: analysis of the MACS/WIHS combined cohort study (MWCCS)

Catie Wiener, Valentina Stosor, Jodie A. Dionne, Stephen J Gange et al.
Respiratory Research
Pneumocystis jirovecii pneumonia detection and treatment
article

Associations between serological evidence of SARS-CoV-2 infection and longitudinal pulmonary outcomes among people with HIV: analysis of the MACS/WIHS combined cohort study (MWCCS)

Catie Wiener, Valentina Stosor, Jodie A. Dionne, Stephen J Gange, M. Bradley Drummond, Catalina Ramirez, Lakshmanane Premkumar, Michelle A Floris-Moore, Alicia E Diggs, Meredith C McCormack, Divya B Reddy, Igor Z Barjaktarevic, Ken M Kunisaki, Beverly E Sha, Stephen R Cole, Robert F Foronjy, Maria L Alcaide, Andrew Edmonds, Deepa G Lazarous, Laurence Huang, Alison Morris, Sushma K Cribbs
article en

Abstract

Among individuals with serologic evidence of SARS-CoV-2 infection, HIV serostatus was not associated with greater declines in pulmonary function or worsening of respiratory symptoms. Our findings suggest that having HIV alone may not increase the risk for pulmonary impairments following a SARS-CoV-2 infection. Further research is needed to understand how uncontrolled HIV infection and severity of SARS-CoV-2 infection may increase risks of adverse pulmonary outcomes following a SARS-CoV-2 infection.

Respiratory ResearchVol. 27(1)
Northwestern University (US), University of North Carolina at Chapel Hill (US), Rush University Medical Center (US), Albert Einstein College of Medicine (US), Johns Hopkins University (US), University of Miami (US), Emory University (US), University of California, Los Angeles (US), University of Pittsburgh (US), SUNY Downstate Health Sciences University (US), Georgetown University (US), University of Alabama at Birmingham (US), Boise VA Medical Center (US), University of St. Francis (US)
Northwestern University, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 66%
Pneumocystis jirovecii pneumonia detection and treatment
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