Pivotal role of interleukin 27 serum level and missense variant (rs181206) in multiple sclerosis
TT genotype and T allele can increase the risk of developing MS. On the other hand, carrying the C allele may be associated with a lower risk of MS development. Understanding IL27 genetics and epistatic interactions can help clarify IL27's role in MS pathogenesis and utilize it as a therapeutic target.
Authors
- Sanaa S. Hamam (ORCID: https://orcid.org/0000-0003-1239-4898)
- Amany E. Elashkar (ORCID: https://orcid.org/0000-0001-8880-9426)
- M. E. Khalil
- Eman Samy
- Mona S. Elkholy
- Amira Samy Elmaghraby
Institutions
- Menoufia University (EG)
Publication Details
- Journal
- Journal of Immunoassay and Immunochemistry
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1080/15321819.2026.2623279
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00