BK polyomavirus-associated progressive multifocal leukoencephalopathy following mogamulizumab therapy for erythrodermic mycosis fungoides
This is the first documented case of BKPyV-associated PML in a Mogamulizumab-treated patient. These findings highlight intra-host heterogeneity at the protein level, possibly reflecting compartment-specific viral evolution, and underscore the need for vigilant BKPyV and JCPyV monitoring during Mogamulizumab treatment.
Authors
- I. Cappuccio (ORCID: https://orcid.org/0000-0001-9245-5499)
- Fabrizio Pane (ORCID: https://orcid.org/0000-0003-2563-4125)
- Stefano Brusa (ORCID: https://orcid.org/0000-0001-6666-836X)
- Michele Longo
- R Sorrentino
- Fabiana Napolitano
- Alessandro Severino
- Luca Vallefuoco
- Giuseppe Portella
- Nicola Simeone
- Lorenzo Esposito
- Cinzia Valeria Russo
- Antonio Esposito
- Rosy D’Agostino
- Serena Molino
- Ugo de Martino
Institutions
- Federico II University Hospital (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.3389/fcimb.2026.1733473
- Citations
- 1
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 24.20
Funders
- Regione Campania