Long-term outcomes of baseline grey-zone patients with HBeAg-negative chronic hepatitis B virus infection

The outcomes of patients with grey-zone HBeAg-negative chronic HBV infection remain uncertain, hindering their optimal management and timely treatment in clinical practice. Our real-world data from a tertiary HBV center provide valuable insights to guide the management of this patient group. Grey-zone HBeAg-negative patients represent a substantial proportion of the chronic HBV population and require careful monitoring, as they are at increased risk of hepatocellular carcinoma and other liver-related events.

Authors

Institutions

Publication Details

Journal
JHEP Reports
Published
2026-02-04
DOI
https://doi.org/10.1016/j.jhepr.2026.101771
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Long-term outcomes of baseline grey-zone patients with HBeAg-negative chronic hepatitis B virus infection

Sofia Paraskevopoulou, Paraskevi Fytili, Dimitrios S. Karagiannakis, Alkistis Papatheodoridi et al.
JHEP Reports
Hepatitis B Virus Studies
article

Long-term outcomes of baseline grey-zone patients with HBeAg-negative chronic hepatitis B virus infection

Sofia Paraskevopoulou, Paraskevi Fytili, Dimitrios S. Karagiannakis, Alkistis Papatheodoridi, Stratigoula Sakellariou, George Papatheodoridis, Ioannis Vlachogiannakos, Panagiota Ioannidou, Margarita Papatheodoridi, Evangelos Cholongitas
article en

Abstract

The outcomes of patients with grey-zone HBeAg-negative chronic HBV infection remain uncertain, hindering their optimal management and timely treatment in clinical practice. Our real-world data from a tertiary HBV center provide valuable insights to guide the management of this patient group. Grey-zone HBeAg-negative patients represent a substantial proportion of the chronic HBV population and require careful monitoring, as they are at increased risk of hepatocellular carcinoma and other liver-related events.

JHEP ReportsVol. 8(4)
National and Kapodistrian University of Athens (GR), Laiko General Hospital of Athens (GR)
Good health and well-being
Openalex Percentile: Top 66%
Hepatitis B Virus Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Long-term outcomes of baseline grey-zone patients with HBeAg-negative chronic hepatitis B virus infection — Sofia Paraskevopoulou, Paraskevi Fytili, et al. · JHEP Reports (2026) | TGRS Research Map | TGRS