Dysregulated miRNAs and downstream gene expression associated with poor treatment response in first-episode psychosis

Our multi-omics approach helps identify miRNAs and their downstream target genes associated with FEP patients' poor responses to antipsychotics, highlighting potential biomarkers for personalized therapy.

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Publication Details

Journal
Brain Behavior & Immunity - Health
Published
2026-02-04
DOI
https://doi.org/10.1016/j.bbih.2026.101190
Primary Topic
MicroRNA in disease regulation
Type
article
Field-Weighted Citation Impact
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article

Dysregulated miRNAs and downstream gene expression associated with poor treatment response in first-episode psychosis

Jen-Pang Wang, Shun-Chun Yu, Charlotte I. Wang, Jenq‐Yuh Ko et al.
Brain Behavior & Immunity - Health
MicroRNA in disease regulation
article

Dysregulated miRNAs and downstream gene expression associated with poor treatment response in first-episode psychosis

Jen-Pang Wang, Shun-Chun Yu, Charlotte I. Wang, Jenq‐Yuh Ko, Tsung-Tsair Yang, Chen-Chung Liu, Sung-Liang Yu, Wei J. Chen, Hsiu-Ping Lin, Ya-Wen Jen, Yi-Ling Chien, Chian-Jue Kuo, Ming H. Hsieh, Yi-Ting Lin, Hsuan-Yu Chen, Hung-Yu Chan, Ya-Wen Shih, Yun-Chu Wang, Chih-Min Liu
article en

Abstract

Our multi-omics approach helps identify miRNAs and their downstream target genes associated with FEP patients' poor responses to antipsychotics, highlighting potential biomarkers for personalized therapy.

Brain Behavior & Immunity - HealthVol. 52
National Health Research Institutes (TW), National Taiwan University (TW), Taipei City Hospital (TW), National Institute of Public Health (LA), Bali Psychiatric Center (TW), National Taiwan University Hospital (TW), Institute of Statistical Science, Academia Sinica (TW), National Defense Medical Center (TW)
No poverty
Openalex Percentile: Top 68%
MicroRNA in disease regulation
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Dysregulated miRNAs and downstream gene expression associated with poor treatment response in first-episode psychosis — Jen-Pang Wang, Shun-Chun Yu, et al. · Brain Behavior & Immunity - Health (2026) | TGRS Research Map | TGRS