Implementing a Program of Comprehensive Tuberculosis Preventive Treatment: Safety, Effectiveness, and Acceptability of Moxifloxacin or Bedaquiline Use for Contacts Exposed to Drug-Resistant Strains

Preventive therapy for drug-resistant TB, including fluoroquinolone-resistant strains, is acceptable, safe, and effective. Implementation of comprehensive TPT programs in high-burden DR-TB settings can protect contacts and reduce transmission.

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Publication Details

Journal
Clinical Infectious Diseases
Published
2026-01-22
DOI
https://doi.org/10.1093/cid/ciaf701
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Implementing a Program of Comprehensive Tuberculosis Preventive Treatment: Safety, Effectiveness, and Acceptability of Moxifloxacin or Bedaquiline Use for Contacts Exposed to Drug-Resistant Strains

Grigory Volchenkov, Einar Heldal, Alexandra V. Solovyeva, Sven Gudmund Hinderaker et al.
Clinical Infectious Diseases
Tuberculosis Research and Epidemiology
article

Implementing a Program of Comprehensive Tuberculosis Preventive Treatment: Safety, Effectiveness, and Acceptability of Moxifloxacin or Bedaquiline Use for Contacts Exposed to Drug-Resistant Strains

Grigory Volchenkov, Einar Heldal, Alexandra V. Solovyeva, Sven Gudmund Hinderaker, Salmaan Keshavjee, Tatiana R. Somova, O. Ponomarenko, Tatiana A. Kuznezova, Evgenia V Belova
article en

Abstract

Preventive therapy for drug-resistant TB, including fluoroquinolone-resistant strains, is acceptable, safe, and effective. Implementation of comprehensive TPT programs in high-burden DR-TB settings can protect contacts and reduce transmission.

Clinical Infectious Diseases
Brigham and Women's Hospital (US), Partners In Health (US), Lovisenberg Diakonale Høgskole (NO), Vladimir State University (RU), Scientific Research Institute of Healthcare Organization and Medical Management (RU), Vladimir Law Institute (RU), Harvard Global Health Institute (US), Vladimir Institute of Business (RU), University of Bergen (NO)
Good health and well-being
Openalex Percentile: Top 66%
Tuberculosis Research and Epidemiology
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