Mutational insights and in silico characterization of NEK family kinases in OSCC patients from the Pakistani population
Collectively, these findings suggest <i>NEK</i> mutations as candidate drivers of OSCC pathogenesis, underscoring their potential as prognostic biomarkers and therapeutic targets, particularly in tobacco-associated disease.
Authors
- Amjad Ali (ORCID: https://orcid.org/0000-0001-8157-576X)
- Sadia Fatima (ORCID: https://orcid.org/0000-0002-1677-5535)
- Muhammad Uzair Khan (ORCID: https://orcid.org/0000-0002-0557-2900)
- Fouzia Nawab (ORCID: https://orcid.org/0000-0002-0474-6737)
- Ishaq Khan (ORCID: https://orcid.org/0000-0001-6110-9403)
- Haseena Nawaz
- Aamir Mehmood
- Wafa Naeem
- Ali Talha Khalil
- Hilal Ahmad
- Ishtiaq Ahmad Khan
- Mohammed Alorini
- Sadia Nawab
- Muhammad Irfan
Institutions
- University of Nottingham Ningbo China (CN)
- Qassim University (SA)
- Shanghai Jiao Tong University (CN)
- University of Karachi (PK)
- Khyber Medical University (PK)
- Lady Reading Hospital (PK)
- University of Glasgow (GB)
- South China University of Technology (CN)
- University of Sheffield (GB)
Publication Details
- Journal
- Frontiers in Bioinformatics
- Published
- 2026-02-04
- DOI
- https://doi.org/10.3389/fbinf.2025.1750649
- Primary Topic
- Microtubule and mitosis dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Karachi
- Higher Education Commision, Pakistan
- Directorate for Biological Sciences