Guideline on the emergency management of critical bleeding in patients with immune thrombocytopenia
Motivated by the life-threatening nature of the condition, the panel made strong recommendations for the combined use of high-dose corticosteroids, high-dose IVIG, platelet transfusions, tranexamic acid, and TPO-RAs for the emergency management of adults and children with a critical ITP bleed.
Authors
- Dimpy Modi (ORCID: https://orcid.org/0000-0002-5879-4179)
- Gail Strachan
- Jennifer DiRaimo (ORCID: https://orcid.org/0000-0001-7033-1647)
- Saifur Rahman Chowdhury (ORCID: https://orcid.org/0000-0003-4361-0792)
- R. F. Grace
- Carolyn E Beck
- Vicky Rowena Breakey (ORCID: https://orcid.org/0000-0001-5168-0243)
- Dale Paynter
- Barbara Pruitt
- S C Porter
- Laura Molnar
- Matthew Kang (ORCID: https://orcid.org/0000-0001-7875-4468)
- Adam Cuker
- Donald Arnold
- Gordon H Guyatt
- Justin W Yan
- Kathryn Elizabeth Webert
- Clare O'Connor
- Menaka Pai
Institutions
- Western University (CA)
- University of Toronto (CA)
- Joseph Brant Hospital (CA)
- American Orchid Society (US)
- Clinical Research of South Florida (US)
- Institute of Aviation Medicine (CZ)
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
- St. Joseph’s Healthcare Hamilton (CA)
- University of Pennsylvania (US)
- University of Cincinnati Medical Center (US)
- Canadian Blood Services (CA)
- McMaster University (CA)
Publication Details
- Journal
- Blood Advances
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1182/bloodadvances.2025018818
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canadian Blood Services
- Health Canada
- Canadian Institutes of Health Research