Patatin‐Like Phospholipase Domain Containing 3 <scp>I</scp> 148 <scp>M</scp> Variant Affects Hepatocellular Carcinoma Recurrence After Liver Resection

Patients with the PNPLA3 CG/GG genotype, especially those with progressive fibrosis, have a high risk of recurrence after liver resection. PNPLA3 genotyping may help identify patients at high risk of late recurrence who require careful long-term surveillance.

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Publication Details

Journal
Liver International
Published
2026-02-04
DOI
https://doi.org/10.1111/liv.70531
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

Patatin‐Like Phospholipase Domain Containing 3 I 148 M Variant Affects Hepatocellular Carcinoma Recurrence After Liver Resection

Takeo Toshima, Kazuki Takeishi, Junya Mita, Yuki Nakayama et al.
Liver International
Liver Disease Diagnosis and Treatment
article

Patatin‐Like Phospholipase Domain Containing 3 I 148 M Variant Affects Hepatocellular Carcinoma Recurrence After Liver Resection

Takeo Toshima, Kazuki Takeishi, Junya Mita, Yuki Nakayama, Takahiro Tomiyama, Takashi Motomura, Yuriko Tsutsui, Shinji Itoh, Alejandro Soto‐Gutierrez, Takuma Ishikawa, Tomoharu Yoshizumi, Kyohei Yugawa, Takeshi Kurihara, Katsuya Toshida
article en

Abstract

Patients with the PNPLA3 CG/GG genotype, especially those with progressive fibrosis, have a high risk of recurrence after liver resection. PNPLA3 genotyping may help identify patients at high risk of late recurrence who require careful long-term surveillance.

Liver InternationalVol. 46(3)
Kyushu University (JP), University of Pittsburgh (US), National Kyushu Medical Center (JP), University of Pittsburgh Medical Center (US)
Good health and well-being
Openalex Percentile: Top 66%
Liver Disease Diagnosis and Treatment
DOISourceOpenAlex
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Patatin‐Like Phospholipase Domain Containing 3 <scp>I</scp> 148 <scp>M</scp> Variant Affects Hepatocellular Carcinoma Recurrence After Liver Resection — Takeo Toshima, Kazuki Takeishi, et al. · Liver International (2026) | TGRS Research Map | TGRS