Detection of Endothelial Plaque in Microbial Keratitis Using Anterior Segment Optical Coherence Tomography

Slit lamp examination substantially under-detects endothelial plaque compared to ASOCT, while ASOCT enables reproducible detection with excellent intra- and inter-grader agreement. These findings support incorporation of ASOCT imaging into microbial keratitis evaluation protocols. Differences in round and flat endothelial plaque morphologies warrant further investigation.

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Publication Details

Journal
medRxiv
Published
2026-02-04
DOI
https://doi.org/10.64898/2026.02.03.26345494
Primary Topic
Ocular Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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OCT
article

Detection of Endothelial Plaque in Microbial Keratitis Using Anterior Segment Optical Coherence Tomography

Gautam Singh Parmar, Folahan Adesola Ibukun, Nakul Singh Shekhawat
medRxiv
Ocular Infections and Treatments
article

Detection of Endothelial Plaque in Microbial Keratitis Using Anterior Segment Optical Coherence Tomography

Gautam Singh Parmar, Folahan Adesola Ibukun, Nakul Singh Shekhawat
article en

Abstract

Slit lamp examination substantially under-detects endothelial plaque compared to ASOCT, while ASOCT enables reproducible detection with excellent intra- and inter-grader agreement. These findings support incorporation of ASOCT imaging into microbial keratitis evaluation protocols. Differences in round and flat endothelial plaque morphologies warrant further investigation.

medRxiv
Johns Hopkins University (US), Johns Hopkins Medicine (US), Mahatma Gandhi Chitrakoot Gramodaya Vishwavidyalaya (IN)
National Institutes of Health
No poverty
Openalex Percentile: Top 67%
Ocular Infections and Treatments
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