The INVasiveness in Pituitary ADEnomas Score: Development and Validation of a Novel Radiographic Grading Scale for Pituitary Adenoma Invasion
We present a novel scale to assess global radiographic invasiveness in pituitary adenomas. The INVADE score demonstrated strong inter-rater reliability and nearly perfect intra-rater reliability. High INVADE scores correlated with significantly lower volumetric EOR. Our results suggest that the INVADE score may be useful for future clinical and research applications.
Authors
- Matthew Poturalski (ORCID: https://orcid.org/0000-0002-8984-3949)
- James Evans
- Divya Yogi-Morren (ORCID: https://orcid.org/0000-0001-5248-9416)
- Jonathan Lee (ORCID: https://orcid.org/0000-0002-5955-5145)
- Varun R. Kshettry (ORCID: https://orcid.org/0000-0003-3217-8279)
- Tamia Potter (ORCID: https://orcid.org/0000-0001-7599-233X)
- João Paulo Almeida (ORCID: https://orcid.org/0000-0002-9930-3807)
- Volodymyr Statsevych (ORCID: https://orcid.org/0000-0003-2991-4730)
- Pranay Soni (ORCID: https://orcid.org/0000-0003-0270-6915)
- Pablo F. Recinos
Institutions
- Cleveland Clinic (US)
- Vanderbilt University (US)
- Thomas Jefferson University Hospital (US)
- Cleveland Clinic Lerner College of Medicine (US)
- Neurological Surgery (US)
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Operative Neurosurgery
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1227/ons.0000000000001916
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00