Maternal Adiposity and DNA Methylation of TfR2 and HJV Genes in Early Pregnancy: Mediating Role of Inflammation and Consequences for Iron Status
Maternal adiposity is associated with epigenetic alterations in the iron metabolism genes TfR2 and HJV in early pregnancy, with modifications in HJV appearing to be mediated by inflammatory pathways.
Authors
- Dr Maria S Mulhern
- Rachelle E Irwin (ORCID: https://orcid.org/0000-0002-6137-1716)
- Mary McCann
- Maeve A. Kerr
- Kazi L. Rahman
- Mark Ledwidge
- Caroline Conway
- Sabrina P. Demirdjian
- Edna P. Rodriguez
- Paul D. Thompson
Institutions
- University College Dublin (IE)
- University of Ulster (GB)
Publication Details
- Journal
- Journal of Nutrition
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1016/j.tjnut.2026.101393
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00