Redefining Pituitary Neuroendocrine Tumors in MEN1: Prevalence, Clinical Behavior, and Implications for Long-Term Surveillance
In our MEN1 cohort, PitNETs were frequent but largely indolent, with a predominance of microadenomas and limited need for surgery. Our findings support individualized, subtype-driven surveillance strategies, with conservative management for clinically non-functioning microadenomas and closer monitoring of prolactin-secreting PitNETs due to variable medical responsiveness.
Authors
- Elio Benevento (ORCID: https://orcid.org/0000-0002-4489-3651)
- Gianfranco Di Iasi (ORCID: https://orcid.org/0009-0001-9737-9912)
- M. Coletta
- Massimo Di Nola
- Annamaria Colao
- Roberto Minotta
- Roberta Modica
Institutions
- University of Naples Federico II (IT)
Publication Details
- Journal
- Current Oncology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.3390/curroncol33020097
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00