Admission serum tropomyosin 4 levels predict 1-year functional outcomes in acute ischemic stroke
Lower serum TPM4 levels on admission were independently associated with poor functional outcomes at 1 year in AIS patients, suggesting that TPM4 may serve as a potential biomarker for long-term outcomes and offer insights into its potential role in stroke pathophysiology. These findings need to be further verified in external cohorts.
Authors
- Chen Yaqi (ORCID: https://orcid.org/0000-0003-3414-3061)
- Yuyi Zhu (ORCID: https://orcid.org/0000-0003-4311-6831)
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- Shihong Zhang (ORCID: https://orcid.org/0000-0002-9661-1089)
- Deren Wang
- Keying Wu
- Mingxi Chen
- Xinyi Leng
- Zilong Hao
Institutions
- Chinese University of Hong Kong (HK)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Sichuan University of Science and Engineering (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2026-02-04
- DOI
- https://doi.org/10.7717/peerj.20745
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00