Integrating genomic and exposomic data identifies endocrine disruptors potentially associated with chronic obstructive pulmonary disease

This integrative translational exposomics framework identifies genetically supported links between EDC-related genes and COPD risk. The findings provide mechanistic insights into how environmental endocrine disruptors may contribute to COPD pathogenesis and offer prioritized molecular targets for future experimental validation and environmental health interventions.

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Publication Details

Journal
Human Genomics
Published
2026-02-04
DOI
https://doi.org/10.1186/s40246-026-00908-z
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Integrating genomic and exposomic data identifies endocrine disruptors potentially associated with chronic obstructive pulmonary disease

Sihan Song, Xiangting Ge, Wanyi Shu, Yirong Wang et al.
Human Genomics
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Integrating genomic and exposomic data identifies endocrine disruptors potentially associated with chronic obstructive pulmonary disease

Sihan Song, Xiangting Ge, Wanyi Shu, Yirong Wang, Jinduo Dong, Yanggang Hong
article en

Abstract

This integrative translational exposomics framework identifies genetically supported links between EDC-related genes and COPD risk. The findings provide mechanistic insights into how environmental endocrine disruptors may contribute to COPD pathogenesis and offer prioritized molecular targets for future experimental validation and environmental health interventions.

Human GenomicsVol. 20(1)
Wenzhou Medical University (CN), Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Openalex Percentile: Top 69%
Chronic Obstructive Pulmonary Disease (COPD) Research
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Integrating genomic and exposomic data identifies endocrine disruptors potentially associated with chronic obstructive pulmonary disease — Sihan Song, Xiangting Ge, et al. · Human Genomics (2026) | TGRS Research Map | TGRS