Psychological and Psychosocial Interventions for People With Schizophrenia and Co-Occurring Substance Use Disorders

The findings of this systematic review and meta-analysis suggest that current psychological and psychosocial interventions provide limited benefit in reducing symptoms and no effect in reducing substance use in individuals with schizophrenia and SUD compared to control conditions, with the exception of nicotine use, highlighting the urgent need to develop more effective treatment strategies.

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Publication Details

Journal
JAMA Psychiatry
Published
2026-02-04
DOI
https://doi.org/10.1001/jamapsychiatry.2025.4390
Primary Topic
Substance Abuse Treatment and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Psychological and Psychosocial Interventions for People With Schizophrenia and Co-Occurring Substance Use Disorders

Emilia Herlitzius, Alexandra Schütz, Josef Priller, Spyridon Siafis et al.
JAMA Psychiatry
Substance Abuse Treatment and Outcomes
article

Psychological and Psychosocial Interventions for People With Schizophrenia and Co-Occurring Substance Use Disorders

Emilia Herlitzius, Alexandra Schütz, Josef Priller, Spyridon Siafis, Stefan Leucht, Nurul Husna Salahuddin, Irene Bighelli
article en

Abstract

The findings of this systematic review and meta-analysis suggest that current psychological and psychosocial interventions provide limited benefit in reducing symptoms and no effect in reducing substance use in individuals with schizophrenia and SUD compared to control conditions, with the exception of nicotine use, highlighting the urgent need to develop more effective treatment strategies.

JAMA Psychiatry
German Center for Neurodegenerative Diseases (DE), German Center for Infection Research (DE), UK Dementia Research Institute (GB), German Centre for Cardiovascular Research (DE), Technical University of Munich (DE), University of Edinburgh (GB)
Good health and well-being
Openalex Percentile: Top 66%
Substance Abuse Treatment and Outcomes
DOIOpen Access PDFOpenAlex
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Psychological and Psychosocial Interventions for People With Schizophrenia and Co-Occurring Substance Use Disorders — Emilia Herlitzius, Alexandra Schütz, et al. · JAMA Psychiatry (2026) | TGRS Research Map | TGRS