Integrated single-cell and transcriptomic profiling identifies machine-learning–based pyroptosis biomarkers in IBD
Pyroptosis is highly active in specific immune and epithelial cells in IBD. Six identified genes show potential as non-invasive diagnostic biomarkers, offering insights into disease mechanisms and therapeutic targets.
Authors
- Jinjiao Li (ORCID: https://orcid.org/0000-0002-6961-2756)
- Yahui Lin
- Yao Lu
- Huan Sai
- Cheng Chen
- Yuansen Li
Institutions
- Kunming Medical University (CN)
- People’s Hospital of Wenshan Prefecture (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.3389/fimmu.2026.1761476
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00