Association of Elevated Thyroid-Stimulating Hormone With Structural Progression in Keratoconus

Elevated TSH is associated with structural progression markers in keratoconus, suggesting a systemic thyroid contribution to disease evolution. While causality is not established, these findings support endocrine screening in early or progressive keratoconus cases and warrant further mechanistic investigation.

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Publication Details

Journal
Cornea
Published
2026-01-22
DOI
https://doi.org/10.1097/ico.0000000000004103
Primary Topic
Corneal surgery and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of Elevated Thyroid-Stimulating Hormone With Structural Progression in Keratoconus

L Stival, Marcony R Santhiago
Cornea
Corneal surgery and disorders
article

Association of Elevated Thyroid-Stimulating Hormone With Structural Progression in Keratoconus

L Stival, Marcony R Santhiago
article en

Abstract

Elevated TSH is associated with structural progression markers in keratoconus, suggesting a systemic thyroid contribution to disease evolution. While causality is not established, these findings support endocrine screening in early or progressive keratoconus cases and warrant further mechanistic investigation.

Cornea
Universidade de São Paulo (BR), Universidade Federal de Goiás (BR)
Good health and well-being
Openalex Percentile: Top 68%
Corneal surgery and disorders
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Association of Elevated Thyroid-Stimulating Hormone With Structural Progression in Keratoconus — L Stival, Marcony R Santhiago · Cornea (2026) | TGRS Research Map | TGRS